Update – a new version of flash – 10.1.85.3 has been released and can be downloaded from
http://fpdownload.adobe.com/get/flashplayer/current/install_flash_player.exe (non IE browsers)
http://fpdownload.adobe.com/get/flashplayer/current/install_flash_player_ax.exe  (internet explorer)

These are direct downloads that do not use Adobe Download Manager.

Flash – http://www.adobe.com/support/security/bulletins/apsb10-16.html

Critical
vulnerabilities have been identified in Adobe Flash Player version
10.1.53.64 and earlier. These vulnerabilities could cause the
application to crash and could potentially allow an attacker to take
control of the affected system.

Adobe recommends users of Adobe Flash Player 10.1.53.64 and
earlier versions update to Adobe Flash Player 10.1.82.76. Adobe
recommends users of Adobe AIR 2.0.2.12610 and earlier versions update to
Adobe AIR 2.0.3.

Flash Media Server – http://www.adobe.com/support/security/bulletins/apsb10-19.html
Critical
vulnerabilities have been identified in Adobe Flash Media Server (FMS)
3.5.3 and earlier versions and Adobe Flash Media Server (FMS) 3.0.5 and
earlier versions for Windows and UNIX. One of the vulnerabilities
could allow an attacker, who successfully exploits the vulnerability, to
run malicious code on the affected system. Adobe has provided a
solution for the reported vulnerabilities and recommends that users
update their installations to Flash Media Server 3.5.4 or 3.0.6
respectively using the instructions provided below.

Cold Fusion – http://www.adobe.com/support/security/bulletins/apsb10-18.html
An important
vulnerability has been identified in ColdFusion 9.0.1 and earlier
versions for Windows, Macintosh and UNIX. This directory traversal
vulnerability could lead to information disclosure. Adobe recommends
users update their product installation using the instructions provided
below.

Update –
For those of you that wish to avoid the Download manager drama – here are direct links

http://fpdownload.adobe.com/get/flashplayer/current/install_flash_player_ax.exe
http://fpdownload.adobe.com/get/flashplayer/current/install_flash_player.exe